Testicular Cancer

French AFU Cancer Committee Guidelines - Update 2024-2026: Testicular germ cell cancer.

To update the recommendations for the management of germ cell tumours of the testis.

Comprehensive PubMed review from 2022 on the diagnosis, treatment and follow-up of testicular germ cell tumours (TGT), as well as safety of treatments.

Epidemiology and Risk Factors for Testicular Cancer: A Systematic Review.

Testicular germ cell tumors (TGCTs) are globally rare, although incidence significantly varies across global geographic regions and ethnicities. Recent decades have seen an unexplained increase in incidence.

Oncological Outcomes Following Robotic Postchemotherapy Retroperitoneal Lymph Node Dissection for Testicular Cancer: A Worldwide Multicenter Study.

The feasibility and safety of a robotic approach for postchemotherapy retroperitoneal lymph node dissection (PC-RPLND) in testicular cancer have been demonstrated, but data on long-term oncological outcomes of this procedure are limited.

Oncological microdissection testicular sperm extraction (Onco-microTESE) outcomes for fertility preservation of patients with testicular cancer with azoospermia or severe oligoasthenoteratozoospermia.

To determine the success rate of oncological microdissection testicular sperm extraction (onco-microTESE) in patients with testicular cancer (TC) with azoospermia and severe oligoasthenoteratozoospermia (OAT; <1 million/mL sperm) and to explore any factors that may predict success.

Late side effects of testicular cancer and treatment: a comprehensive review.

Testicular cancer is a rare solid organ tumour associated with high cure rates and young age at diagnosis, hence it has a sizeable cohort of survivors worldwide. As it is one of the earliest tumours to be cured, a lot of studies have highlighted the late side effects of cancer and its different treatment modalities including surgery, radiotherapy and chemotherapy.

Incidence of Erectile Dysfunction and Testosterone Deficiency in Testicular Cancer Survivors - Beyond the Abstract

The idea for our recent publication in the Journal of Urology stemmed from a growing concern for the quality of life in Testicular Cancer (TCa) survivors.1 Erectile dysfunction (ED) and testosterone deficiency (TD) have surfaced as two significant men’s health disorders that negatively affect these patients long after they complete their cancer treatment.2,3 However, the specific pathogenesis and long-term impact of these conditions remain underexplored. Our study sought to fill this gap by evaluating the incidence and potential drivers of ED and TD in a large cohort of U.S. Veterans diagnosed with TCa.

Insurance remains a major source of disparity for patients with testicular cancer: call for advocacy.

To evaluate the effects of socioeconomic factors, including insurance status, on treatment and survival for patients with testicular cancer.

We extracted a retrospective cohort from the National Cancer Database that included patients diagnosed with testicular cancer 2004-2020.

Epithelioid trophoblastic tumor in male patients with germ cell tumor: A clinicopathologic analysis of five cases.

Epithelioid trophoblastic tumor (ETT) is an extremely rare chorionic-type neoplasm in the testis, with only seven cases reported in the literature. Here, we report five cases of testicular ETT from a single institution, constituting the largest series of this rare tumor to date.

Longitudinal trends in testicular volume z scores from puberty to adulthood, sperm quality, and paternity outcomes after childhood cancer.

Childhood cancer therapy may cause subfertility. This study correlated cancer therapy exposures with testicular volumes from puberty to adulthood, spermatogenesis, and paternity outcomes in adulthood.

Genomic landscape of adult testicular germ cell tumours in the 100,000 Genomes Project.

Testicular germ cell tumours (TGCT), which comprise seminoma and non-seminoma subtypes, are the most common cancers in young men. In this study, we present a comprehensive whole genome sequencing analysis of adult TGCTs.