AUA 2014

auaAmerican Urological Association (AUA)
Annual Meeting
May 16 - 21, 2014

Orlando, Florida USA

#AUA14 - Magnetic resonance imaging/ultrasound-fusion biopsy better predicts whole gland pathology on radical prostatectomy compared to standard 12-core biopsy - Session Highlights

ORLANDO, FL USA (UroToday.com) - In men suspected of having prostate cancer, the current standard is ultrasound-guided template 12-core biopsy to determine the grade and relative burden of disease.

#AUA14 - Rectal culture prior to prostate biopsy identifies men at risk for infection: A multi-institutional international collaborative study - Session Highlights

ORLANDO, FL USA (UroToday.com) - At the infection/inflammation poster session, Dr. Michael Liss discussed a timely issue of fecal carriage of fluoroquinolone resistance and prostate biopsy infection.

#AUA14 - Clinical characterization, management, and outcome of adrenal pheochromocytoma in von Hippel-Lindau families - Session Highlights

ORLANDO, FL USA (UroToday.com) - Pheochromocytoma is more common in familial cancer syndromes, including von Hippel-Lindau (vHL) disease.

#AUA14 - Multiparametric MRI characteristics of patients upgraded by MRI/ultrasound fusion guided biopsy across PSA-based cutoffs - Session Highlights

ORLANDO, FL USA (UroToday.com) - While multiple studies over the past several years have highlighted a role for multi-parametric prostate MRI and MRI-ultrasound fusion biopsy in evaluating men with prostate cancer, these modalities remain expensive and are not yet in widespread use.

#AUA14 - Differential gene expression in responsive versus recurrent non-muscle invasive high-grade urothelial carcinomas after induction BCG - Session Highlights

ORLANDO, FL USA (UroToday.com) - Although BCG remains the intravesical therapy of choice, after TURBT, for high-grade non-muscle invasive bladder carcinomas (NMIBC), a recurrence and progression rate of up to 40% occurs after induction treatment. BCG failure likely can be attributed, at least partially, to inherent tumoral characteristics.

#AUA14 - The oxidative stress response of urothelial carcinoma cells to BCG exposure - Session Highlights

ORLANDO, FL USA (UroToday.com) - Cellular oxidative stress (COS), post BCG treatment, plays a central role in mediating direct effect of BCG on urothelial carcinoma (UC) cells.

#AUA14 - Histologic analysis of tumor-parenchyma interface in patients with renal neoplasms - Session Highlights

ORLANDO, FL USA (UroToday.com) - The oncological propriety of enucleative or ‘minimal-margin’ partial nephrectomy (PN) close to the tumor edge remains debatable. The research group analyzed histo-pathologic data to objectively characterize the tumor-parenchyma interface as regards the tumor pseudo-capsule (PC), adjacent parenchyma, and intra-renal arteries.

#AUA14 - Improving renal needle-biopsy accuracy with RCC-specific DNA methylation markers - Session Highlights

ORLANDO, FL USA (UroToday.com) - The detection of small renal masses (SRMs) < 4cm in size have given rise to the widespread use of abdominal imaging.

#AUA14 - Quantification of renal cell optical biomarkers using second harmonic generation imaging - Session Highlights

ORLANDO, FL USA (UroToday.com) - Given the significance of second harmonic generation (SHG)-based optical biomarkers in various cancers—including ovarian and breast cancer—these authors sought to examine whether this application might also be useful in renal cell carcinoma (RCC).

#AUA14 - Cell cycle progression score predicts metastatic progression of clear cell renal cell carcinoma after resection - Session Highlights

ORLANDO, FL USA (UroToday.com) - When detecting organ-confined disease, clear cell renal cell carcinoma (ccRCC) is primarily treated surgically, however, close follow-up should aim to detect recurrence.