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- Sam Chang speaks with Mark Tyson about the BOND-003 trial's findings on cretostimogene grenadenorepvec for treating BCG unresponsive carcinoma in situ of the bladder. Dr. Tyson explains the dual-action mechanism of the drug, combining direct tumor cell destruction with enhanced immune response activation. Impressively, the trial shows a 75.2% complete response rate at various time points with a ti...
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- Ashish Kamat introduces Stephen B. Williams who discusses findings from his study on blue light cystoscopy in bladder cancer treatment, conducted within the VA healthcare system. The study utilized a propensity score-matched analysis to compare the outcomes of blue light versus white light cystoscopy, focusing on bladder cancer recurrence, progression, and overall survival. The analysis revealed s...
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- Ashish Kamat hosts Sam Chang to discuss the SunRISe-3 trial. Dr. Chang presents the ongoing trial investigating the efficacy of TAR-200, either alone or combined with cetrelimab, against BCG in treating patients with BCG-naive bladder cancer. TAR-200, a targeted release system using gemcitabine, is tested for its potential benefits over traditional treatments due to its unique delivery system aime...
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- Andrei Cumpanas presented a study on the impact of irrigation fluid temperature on thulium fiber laser stone ablation, finding that while higher fluid temperatures were associated with increased ablation cone volume, the clinical significance was minimal compared to an increase in laser energy. Biography: Andrei D. Cumpanas, MD, Researcher, Department of Urology, The University of California, Irvi...
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- Bruce Gao presented research on Electromotive Drug Administration in the Porcine Ureter, demonstrating its potential to enhance drug delivery and ureteral distensibility, offering new insights into acute ureteral dilation. Biographies: Bruce M. Gao, MD, Urologist, University of California Irvine, Irvine, CA Read the Full Video Transcript {article title="4003-i-aua-pd10-02-in-vivo-acute-ureteral-di...
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- Andrei Cumpanas presented a study on ureteral strictures following ureteroscopic ureteral wall injury, highlighting a previously unidentified concern. The study aimed to determine the risk of post-ureteroscopic ureteral stricture formation based on the depth of injury into the ureteral wall, revealing that stricture rates increase significantly when the ureteral wall is partially or fully transgre...
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- Andrei Cumpanas from UC Irvine presented a study on using immersive virtual reality (IVR) models prior to percutaneous stone removal, showing that IVR improved surgeon understanding of case anatomy, altered calyx choice in 30% of cases, and led to better surgical outcomes with reduced complications. Biography: Andrei D. Cumpanas, MD, Researcher, Department of Urology, The University of California,...
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- Andrei Cumpanas presented a study on using an AI convolutional neural network to accurately determine CT-based stone volume, showing that the AI algorithm outperformed traditional ellipsoid formulas in accuracy and precision, especially for larger stones with irregular shapes. Biographies: Andrei D. Cumpanas, MD, Researcher, Department of Urology, The University of California, Irvine, CA Read the...
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- Andrei Cumpanas presented a study on assessing alterations in stone burden among patients with Medullary Sponge Kidney (MSK), showing that CT reports often miss increases in stone volume in MSK patients, leading to a false sense of stable disease. Biography: Andrei D. Cumpanas, MD, Researcher, Department of Urology, The University of California, Irvine, CA Read the Full Video Transcript {article t...
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- Amir Lavasani from UC Irvine presented a study on the force exerted by urologists during ureteral access sheath placement, revealing that a significant percentage apply forces above recommended limits, risking high-grade ureteral injury. Biography: Seyed Amiryaghoub M. Lavasani, Clinical Researcher, Department of Urology, University of California, Irvine, CA Read the Full Video Transcript {article...
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